Showing posts with label Cryosurgery. Show all posts
Showing posts with label Cryosurgery. Show all posts

Monday, 2 July 2012

Interview with Dr Spilken, Cryosurgery specialist for plantar fibromas


Today I have another interview with a specialist, Dr Terry Spilken.

Dr Terry L. Spilken earned his doctorate in podiatric medicine in 1979 at the New York College of Podiatric Medicine. He did his residency training at Kingsbrook Jewish Medical Center and Community Hospital. Within a decade, he was back at the College as a member of the adjunct faculty, climbing the podiatric stairway to the position of Dean of Graduate Medical Education and then Dean of Student Services. He has obtained the rank of Associate Professor in the Division of Medical Science.

He has also worked with the International Dupuytren’s society in the production of the book “Dupuytren’s Disease and related hyperproliferative disorders” where he was author on a chapter on “Cryotherapy and other therapeutic options for plantar fibromatosis” where here covered not only several of the options for the treatment of plantar fibroma’s including cryosurgery and surgery but also the associated risk factors, symptoms and inheritance.

You can find more information here
All information above is provided with permission and is available from the above link.

Here I have questioned him on the above subject of plantar fibromatosis / Ledderhose disease:

1) Do you often come across plantar fibroma’s? How common would you say they are in the USA?

Plantar fibromatosis is a very rare condition.  We see it quite often because of our specialization in treating this condition.

2) What are the risk factors for this disease and do you see these in patients, in particular what percentage of patients tend to have a family history of the disease?

The cause of plantar fibromatosis is still unknown.  There is thought that it is an inherited disease.  The necessary genes may remain dormant in the family over many generations.  Besides family history, there is a higher incidence in males.  Patients with these conditions have a higher risk factor: Dupuytren's disease, Peyronie's disease, epilepsy, other seizure disorders, diabetes mellitus, chronic liver disease and hypothyroidism.

3) I understand that every case is different but what course of treatment do you recommend for early stage Ledderhose?

Patients respond to cryosurgery very successfully the earlier in the course of the condition we get to do the procedure.  Cryosurgery has proven to be a very good option for patients and they seem very happy with the results.

b) Other options I have heard of being used early on include physio and verapamil. Do you know of any cases where these have been successful or the success rate? I ask as I have visited 2 physiotherapist who both said this could not be used to help with this condition and have heard poor results about verapamil.

I have not had success with verapamil.  Research is still being done on this treatment but so far the patient comments have been negative.  I don't think physical therapy is an option at all.  I have not come across any success rate doing PT.

4) I see on your website that you perform cryosurgery, what is this and how does it help with plantar fibroma’s? What sort of success rate does it have and can it be repeated?

Cryosurgery is an ambulatory procedure done in the doctor's office.  It involves freezing of nerve cells performed through a small incision, no sutures are required.  An autoimmune response is created with a change in the protein antigenic properties.  We have about an 80% success rate when the fibromas are in the early stages.  For advanced cases, we repeat the procedure several times until we receive the desired effect.

5) What is the procedure and recovery times for cryosurgery?

A small incision is made on the side of the foot under local anesthesia.  A trochar is used to cut into the fibroma.  The probe is then inserted into the fibroma and ice balls are created to destroy the fibroma.  Patients need 24 hours to elevate and foot and keep the bandage dry.  They need to avoid rigorous activity for about 1 week.  It takes 2 months for the full effectiveness of the procedure but the patient is ambulating fully within a few days.

6) I have also seen on the site that you performed ESWT, I have seen reports linking this to treatment of plantar fibroma’s, is this something that you do or know anything about?


I have not used ESWT for fibromatosis.  We use it for plantar fasciitis.

7) In the book chapter you cover surgical treatment of the disease, what are the options when it comes to surgery?

Removing the lesion alone does not work.  In fact, it has a 90% failure rate.  The only traditional surgery that has a good success rate is a complete fasciotomy.  We remove the entire fascia band so there is no fibrous tissue available for a fibroma to form.  There is a very long recovery time for this painful procedure.  The patient is left without a plantar fascia that can affect their ambulation in the future.  That is the reason why cryosurgery has been so popular as an alternative to this drastic procedure.

8) Do you have any other advice that you would like to give to patients with this condition?

Patients are very educated and do research on their conditions.  That is a wonderful development of the computer age.  The more knowledge the patient gathers the more options they give themselves.  Most doctors are not familiar with plantar fibromatosis and therefore don't know the best treatment choices to offer.  My advice is to keep as current as possible with the options available to them and follow the latest research.

I would again like to thank Dr Spilken for his answers. 

Friday, 23 March 2012

Cryosurgery for the treatment of Ledderhose

Cryosurgery for the treatment of Plantar Fibromas / Plantar Fibromatosis / Ledderhose Disease:

So cryosurgery is a technique where cold temperatures are used to try and relieve the pain. Note that this is not a cure but is a pain management technique. See here for an interview with one of the top specialists for this kind of treatment. 

How and why does cryosurgery help a plantar fibroma / ledderhose disease?: 

I am getting a lot of the information today from the book, Dupuytren's Disease and Related Hyperproliferative disorders - Chapter 49. I have tried to find more information on this technique but it seems that it is not widely used and certainly there are not any long term results in. 

So how does this work?

The principle that freezing for pain management of injuries has long been known but getting the techniques right to use it has taken time but it is now common practice for many people. The technique used here is basically the application of cold temperatures -70oC to the affected tissue, in this case the foot and this causes a block in the nerves which means that pain is not felt.

Results?: 

So results in this were measured by the improvement in pain in 28 patients. After one treatment it was considered a success in 78% of those patients and with a further second treatment it was down to 2 patients that were not happy and they were considered successful after a third treatment. 

Side Effects: 

None were discussed but it was mentioned that this is a quick and easy procedure and does not requiring stitching or any time off of your feet for recovery and can even be repeated within 2 months. 

My Experience: 

Well ok so I have no experience with this but I have found this page where someone shares their experience with this treatment. Bashkar Cryosurgery for Ledderhose He seemed happy with the treatment and says that he thinks he has helped him keep the disease under control.  

Other than the book there is also some information on this page Dupuytren's Online

Monday, 21 November 2011

Treatments for Plantar Fibromas

Over the years I have done a lot of research into the different options available for people with Ledderhose / plantar fibroma's and although there are treatments out there none are a cure. Below are some therapies that might help, I found some of the details for these from http://www.dupuytren-online.info/ledderhose_therapies.html and on the British Dupuytren's Society.

Radiation therapy – 

It is thought that radiation therapy can help stop the progression of the disease however this only works if it is in the earlier stages, if the condition is more developed then it can still help reduce the size of the lump, however of course radiation is not good for your body in general as it can introduce mutations which can lead to cancer. However, in the UK on the NHS at least, the chances of receiving this for Ledderhose disease is very slim as it has not been approved for use on this and also due to very long waiting lists and priority, rightly so, being given to cancer patients. See here for more details. It is available privately and contact me if you want information as this is a procedure that I have had. 

Steroid / Cortizone injections – 

Having had one of these I can say that the administration of the local anaesthetic hurts a lot and then you have a weird sensation of the application of the steroid as you can feel it going in and around the lump but there is no pain or anything, however don’t go back to work afterwards as I did as the local will stop working after a few hours and if you are anything like me you won’t be able to walk and I would also think about taking the next day off as well to help it recover. However these can cause a reduction in size and slow progression an it helped me for about 6 months before everything returned. See here for more detail. 

Cryosurgery – 

Although only use a few times it has had some success. Basically the idea here is to freeze the diseased tissue using deep freezing with something like liquid nitrogen, to be honest having worked with liquid nitrogen this option scares me a little as the stuff used in the wrong way can easily be lethal, though I am sure in the quantities used it is perfectly safe. However there is the known side effect that it can produce hard scar tissue which then results in pain when walking meaning that the end result may not be too different to leaving it alone.  See here for more details.

Surgery – 

This is the one way to actually remove the lump and is sometimes basically the only option left once it is big enough and painful enough. Clearly with the load bearing that the foot has to undertake on a daily basis there are going to be side effects and additional some people have reported that post surgery nodules have grown back quicker and worse than before, meaning that this option needs to be treated as a last resort and with a certain degree of caution, I have seen posts of people saying do not consider this, just do not do it, so is it better to try this and maybe get better or continue as you are? See here for more details.

Verapamil – 

This is a calcium channel blocker that has been used in the treatment of other conditions and it is thought to work by blocking the release of collagen this changes steady state levels of production of collagen and break down by collagenases so that there is more break down to compared to production when means that the levels of collagen, thought to be the main part of the lump, are decreased and thus the size and pain produced are decrease. See here for more details.

Orthotics –

These are basically shoe inserts that take the pressure off of the lump, if they work they are a great treatment as they are non-invasive. See here for detail.

Physiotherapy – 

I have seen online that this can be recommended, however I have been to 2 physios, 1 was NHS and 1 was private and both of them told me there was nothing that they could do to help with this and for me this was just a step in the pathway towards getting proper treatment.

Enzyme Injections (added 2021) - 

In theory not approved in many countries for Ledderhose but there are collagenase injections being used and the treatment used by Dr Davis. 

I hope what I have put here helps someone, if you need more then browse the pages specific for those treatments.