Welcome

Welcome to the Ledderhose disease (plantar fibroma) blog.

My name is Gary and I am the author of this blog. I am a ledderhose patient from the UK. I am an ex-scientist and hold a degree in Molecular Genetics and I try and put this experience to good use exploring this condition.

I have pages here about the treatment options, patient experiences including my own, insights from medical professionals, explanations of the science and whatever else I think may be useful for fellow patients. Through the blog I have made contacts with many patients, professionals and charities and now work as a trustee for the British Dupuytren's Society.

Hopefully you can find the pages you want using the navigation menu above or use the search box to look for specific information.

Hope you enjoy reading the blog and please contact me at ledderhosedisease@gmail.com or leave a message on here to get in touch. All information will be kept private unless you tell me otherwise.

Thank you for visiting.

Friday, 12 November 2021

New Stuff

 I can't say much at the moment but I am hoping that some new work I am collaborating on will be opening up in the new year. It should be a good chance to gathering some information on some patients and to spread the word and information about Ledderhose disease. 

It will be really interesting to see where it goes. In the mean time I am continuing to try and increase the profile of the condition. We had a good catch up with at the BDS recently and Anna has been working hard with Dr Shaffer to create some really good YouTube Content. 

I intend to post a few of these videos, the first is below and is why it might be too early for radiotherapy. 




Saturday, 21 August 2021

Risk Factors for Dupuytrens's

Recently a new article was published around the risk factors for Duputren's and I and by extensions Ledderhose? The article was freely accessible here.

Rydberg, M., Zimmerman, M., Löfgren, J.P. et al. Metabolic factors and the risk of Dupuytren’s disease: data from 30,000 individuals followed for over 20 years. Sci Rep 11, 14669 (2021). https://doi.org/10.1038/s41598-021-94025-7

In summary the article suggests that the 2 metabolic things that are most likely to increase your risk are diabetes and excessive alcohol consumption. Of course the main risk factor is still likely to be some genetic component. I then found another article, also freely available on the following link.

The article is by Dominic Furniss who has close links with the British Dupuytren's Society and has done lots of great work on Dupuytren's in this research at Oxford. This article produced the following table. 



  Nongenetic Factors Associated with Dupuytren’s Disease: A Systematic Review published by Osaid H. Alser, M.D. Rachel Y. L. Kuo, M.B.B.Chir. Dominic Furniss, F.R.C.S.(Plast.) in (Plast. Reconstr. Surg. 146: 799, 2020.)