For those that don't know or remember there has been a very interesting trial taking place for the use of Anti TNF in the treatment of Dupuytrens. The results of the study have now been published and the complete article can be found here: https://www.thelancet.com/
Overall it appears that the trial was successful. The nodules that were injected got softer, and progression stopped. This is potentially very good news for both Dupuytren's and in the longer term Ledderhose patients as long only will it hopefully provide another treatment option for these conditions but suggests that scientists are contining to have a better understanding of the condition.
Additional there is a short video to explain the trial here: https://youtu.be/jyoUkLiUg4Q
There has been a press release which can be found here: https://www.ndorms.ox.ac.uk/
Looking at the results it looks like nodule size and hardness both decreased over time with these injections, both good indicators that the condition is improving with very few adverse issues in response to the treatment. Overall these results look very promising and I look forward to seeing how they progress in the future.
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