Recently a new article was published around the risk factors for Duputren's and I and by extensions Ledderhose? The article was freely accessible here.
Rydberg, M., Zimmerman, M., Löfgren, J.P. et al. Metabolic factors and the risk of Dupuytren’s disease: data from 30,000 individuals followed for over 20 years. Sci Rep 11, 14669 (2021). https://doi.org/10.1038/s41598-021-94025-7
In summary the article suggests that the 2 metabolic things that are most likely to increase your risk are diabetes and excessive alcohol consumption. Of course the main risk factor is still likely to be some genetic component. I then found another article, also freely available on the following link.
The article is by Dominic Furniss who has close links with the British Dupuytren's Society and has done lots of great work on Dupuytren's in this research at Oxford. This article produced the following table.
Nongenetic Factors Associated with Dupuytren’s Disease: A Systematic Review published by Osaid H. Alser, M.D. Rachel Y. L. Kuo, M.B.B.Chir. Dominic Furniss, F.R.C.S.(Plast.) in (Plast. Reconstr. Surg. 146: 799, 2020.)
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